I am tired of the constant, fresh agony of separation; why can't what I desire simply happen just once?

This profound couplet speaks of the weariness of the heart. The poet, Mir Taqi Mir, expresses an exhaustion not with love itself, but with the constant, fresh pain of separation. He feels utterly fatigued by the endless cycle of loss and yearning. He yearns for a singular, definitive resolution—a moment of completeness—rather than the perpetual ache of 'almost.' It is a cry for peace, a desire for destiny to finally reveal itself, just once.